Arginyltransferase ATE1 suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers

Arginylation is an emerging posttranslational modification mediated by arginyltransferase (ATE1) that is essential for mammalian embryogenesis and regulation of the cytoskeleton. Here, we discovered that Ate1 knockout embryonic fibroblasts exhibit tumorigenic properties, including abnormally rapid c...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Rai, Reena, Zhang, Fangliang, Colavita, Kristen, Leu, Nicolae Adrian, Kurosaka, Satoshi, Kumar, Akhilesh, Birnbaum, Michael D., Győrffy, Balázs, Dong, Dawei W., Shtutman, Michael, Kashina, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916053/
https://ncbi.nlm.nih.gov/pubmed/26686093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.473
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