Arginyltransferase ATE1 suppresses cell tumorigenic potential and inversely correlates with metastases in human cancers

Arginylation is an emerging posttranslational modification mediated by arginyltransferase (ATE1) that is essential for mammalian embryogenesis and regulation of the cytoskeleton. Here, we discovered that Ate1 knockout embryonic fibroblasts exhibit tumorigenic properties, including abnormally rapid c...

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Bibliografiset tiedot
Julkaisussa:Oncogene
Päätekijät: Rai, Reena, Zhang, Fangliang, Colavita, Kristen, Leu, Nicolae Adrian, Kurosaka, Satoshi, Kumar, Akhilesh, Birnbaum, Michael D., Győrffy, Balázs, Dong, Dawei W., Shtutman, Michael, Kashina, Anna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4916053/
https://ncbi.nlm.nih.gov/pubmed/26686093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.473
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