Inhibition of local estrogen synthesis in the hippocampus impairs hippocampal memory consolidation in ovariectomized female mice

The potent estrogen 17β-Estradiol (E(2)) plays a critical role in mediating hippocampal function, yet the precise mechanisms through which E(2) enhances hippocampal memory remain unclear. In young adult female rodents, the beneficial effects of E(2) on memory are generally attributed to ovarian-synt...

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Udgivet i:Horm Behav
Main Authors: Tuscher, Jennifer J., Szinte, Julia S., Starrett, Joseph R., Krentzel, Amanda A., Fortress, Ashley M., Remage-Healey, Luke, Frick, Karyn M.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915975/
https://ncbi.nlm.nih.gov/pubmed/27178577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yhbeh.2016.05.001
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