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Human Adenovirus Serotype 3 Vector Packaged by a Rare Serotype 14 Hexon

Recombinant adenovirus serotype 3 (rAd3), which infects cells through the receptor desmoglein 2 (DSG2), has been investigated as a vector for gene therapy or vaccination. However, pre-existing anti-vector immunity may limit the practical application of rAd3. In this study, we investigated the seropr...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Su, Xiaobo, Tian, Xingui, Jiang, Zaixue, Ma, Qiang, Liu, Qian, Lu, Xiaomei, Zhou, Rong
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915686/
https://ncbi.nlm.nih.gov/pubmed/27328032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156984
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