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Early onset of the "on-off" phenomenon in children with symptomatic Parkinsonism.

Many patients with idiopathic Parkinson's disease treated with levodopa for more than five years develop fluctuations in their clinical response to this drug. Such fluctuations may be unpredictable, but more commonly occur in a regular pattern related to the size and timing of the levodopa dosa...

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Autors principals: Lang, A E, Meadows, J C, Parkes, J D, Marsden, C D
Format: Artigo
Idioma:Inglês
Publicat: 1982
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC491565/
https://ncbi.nlm.nih.gov/pubmed/6982310
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