Recombinase-dependent mouse lines for chemogenetic activation of genetically defined cell types

Chemogenetic technologies, including the mutated human Gq-coupled M3 muscarinic receptor (hM3Dq), have greatly facilitated our ability to directly link changes in cellular activity to altered physiology and behavior. Here, we extend the hM3Dq toolkit with recombinase-responsive mouse lines that perm...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Sciolino, Natale R., Plummer, Nicholas W., Chen, Yu-wei, Alexander, Georgia M., Robertson, Sabrina D., Dudek, Serena M., McElligott, Zoe A., Jensen, Patricia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915594/
https://ncbi.nlm.nih.gov/pubmed/27264177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.034
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