Mitigating Meal-Related Glycemic Excursions in an Insulin-Sparing Manner During Closed-Loop Insulin Delivery: The Beneficial Effects of Adjunctive Pramlintide and Liraglutide

OBJECTIVE: Closed-loop (CL) insulin delivery effectively maintains glucose overnight but struggles when challenged with meals. Use of single-day, 30-μg/meal pramlintide lowers meal excursions during CL. We sought to further elucidate the potential benefits of adjunctive agents after 3–4 weeks of out...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Sherr, Jennifer L., Patel, Neha S., Michaud, Camille I., Palau-Collazo, Miladys M., Van Name, Michelle A., Tamborlane, William V., Cengiz, Eda, Carria, Lori R., Tichy, Eileen M., Weinzimer, Stuart A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
The Artificial Pancreas in 2016: A Digital Treatment Ecosystem for Diabetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915555/
https://ncbi.nlm.nih.gov/pubmed/27208332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc16-0089
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