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Should Restrictions Be Relaxed for Metformin Use in Chronic Kidney Disease? No, We Should Never Again Compromise Safety!

Metformin is and has been considered as first-line therapy for type 2 diabetes for over a quarter of a century. Like other biguanides, metformin can cause a lactic acidosis that is exceptionally rare but fatal. The likelihood of metformin-associated lactic acidosis is substantially higher in patient...

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Detalhes bibliográficos
Publicado no:Diabetes Care
Main Authors: Kalantar-Zadeh, Kamyar, Kovesdy, Csaba P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915554/
https://ncbi.nlm.nih.gov/pubmed/27330129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc15-2327
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