Markers of Serotonergic Function in the Orbitofrontal Cortex and Dorsal Raphé Nucleus Predict Individual Variation in Spatial-Discrimination Serial Reversal Learning

Dysfunction of the orbitofrontal cortex (OFC) impairs the ability of individuals to flexibly adapt behavior to changing stimulus-reward (S-R) contingencies. Impaired flexibility also results from interventions that alter serotonin (5-HT) and dopamine (DA) transmission in the OFC and dorsomedial stri...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Barlow, Rebecca L, Alsiö, Johan, Jupp, Bianca, Rabinovich, Rebecca, Shrestha, Saurav, Roberts, Angela C, Robbins, Trevor W, Dalley, Jeffrey W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915245/
https://ncbi.nlm.nih.gov/pubmed/25567428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.335
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