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The preventive effect of resiniferatoxin on the development of cold hypersensitivity induced by spinal nerve ligation: involvement of TRPM8

BACKGROUND: Resiniferatoxin (RTX) is a potent analog of capsaicin and activates transient receptor potential (TRP) vanilloid type (TRPV) 1. In the current study, we investigated the preventive effect of perineural RTX on the development of cold hypersensitivity induced by spinal nerve ligation (SNL)...

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Publicado en:BMC Neurosci
Autores principales: Koh, Won Uk, Choi, Seong-Soo, Kim, Ji Hyun, Yoon, Hye Joo, Ahn, Ho-Soo, Lee, Sun Kyung, Leem, Jeong Gil, Song, Jun Gol, Shin, Jin Woo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915067/
https://ncbi.nlm.nih.gov/pubmed/27329106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-016-0273-8
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