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Adjusting microbiome profiles for differences in microbial load by spike-in bacteria
BACKGROUND: Next-generation 16S ribosomal RNA gene sequencing is widely used to determine the relative composition of the mammalian gut microbiomes. However, in the absence of a reference, this does not reveal alterations in absolute abundance of specific operational taxonomic units if microbial loa...
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| Pubblicato in: | Microbiome |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4915049/ https://ncbi.nlm.nih.gov/pubmed/27329048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40168-016-0175-0 |
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