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Possible selection of host folate pathway gene polymorphisms in patients with malaria from a malaria endemic region in North East India

BACKGROUND: Recent studies in experimental mice have shown that mild deficiency of methylenetetrahydrofolate reductase (MTHFR) enzyme confers protection against malaria, thus providing an important basis for the hypothesis that MTHFR polymorphism, i.e. C677T, might have been subjected to selection p...

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Detalles Bibliográficos
Publicado en:Trans R Soc Trop Med Hyg
Main Authors: Mirgal, Darshana, Ghosh, Kanjaksha, Mahanta, Jagadish, Dutta, Prafulla, Shetty, Shrimati
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914876/
https://ncbi.nlm.nih.gov/pubmed/27198213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/trstmh/trw026
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