Dynamic Changes in Local Protein Synthetic Machinery in Regenerating Central Nervous System Axons after Spinal Cord Injury

Intra-axonal localization of mRNAs and protein synthesis machinery (PSM) endows neurons with the capacity to generate proteins locally, allowing precise spatiotemporal regulation of the axonal response to extracellular stimuli. A number of studies suggest that this local translation is a promising t...

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Bibliographic Details
Published in:Neural Plast
Main Authors: Sachdeva, Rahul, Farrell, Kaitlin, McMullen, Mary-Katharine, Twiss, Jeffery L., Houle, John D.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914735/
https://ncbi.nlm.nih.gov/pubmed/27375904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/4087254
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