Lipoxin A4 Preconditioning Attenuates Intestinal Ischemia Reperfusion Injury through Keap1/Nrf2 Pathway in a Lipoxin A4 Receptor Independent Manner

Oxidative stress plays a critical role in the pathogenesis of intestinal ischemia reperfusion (IIR) injury. Enhancement in endogenous Lipoxin A4 (LXA4), a potent antioxidant and mediator, is associated with attenuation of IIR. However, the effects of LXA4 on IIR injury and the potential mechanisms a...

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Udgivet i:Oxid Med Cell Longev
Main Authors: Han, Xue, Yao, Weifeng, Liu, Zipeng, Li, Haobo, Zhang, Zhong-jun, Hei, Ziqing, Xia, Zhengyuan
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914733/
https://ncbi.nlm.nih.gov/pubmed/27375835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9303606
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