Clinical Efficacy of Polymyxin Monotherapy versus Nonvalidated Polymyxin Combination Therapy versus Validated Polymyxin Combination Therapy in Extensively Drug-Resistant Gram-Negative Bacillus Infections

Polymyxins have emerged as a last-resort treatment of extensively drug-resistant (XDR) Gram-negative Bacillus (GNB) infections, which present a growing threat. Individualized polymyxin-based antibiotic combinations selected on the basis of the results of in vitro combination testing may be required...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cai, Bingxuan, Cai, Yiying, Liew, Yi Xin, Chua, Nathalie Grace, Teo, Jocelyn Qi-Min, Lim, Tze-Peng, Kurup, Asok, Ee, Pui Lai Rachel, Tan, Thuan Tong, Lee, Winnie, Kwa, Andrea Lay-Hoon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914661/
https://ncbi.nlm.nih.gov/pubmed/27090177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03064-15
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