A Silenced vanA Gene Cluster on a Transferable Plasmid Caused an Outbreak of Vancomycin-Variable Enterococci

We report an outbreak of vancomycin-variable vanA(+) enterococci (VVE) able to escape phenotypic detection by current guidelines and demonstrate the molecular mechanisms for in vivo switching into vancomycin resistance and horizontal spread of the vanA cluster. Forty-eight vanA(+) Enterococcus faeci...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Sivertsen, Audun, Pedersen, Torunn, Larssen, Kjersti Wik, Bergh, Kåre, Rønning, Torunn Gresdal, Radtke, Andreas, Hegstad, Kristin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Mechanisms of Resistance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914660/
https://ncbi.nlm.nih.gov/pubmed/27139479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00286-16
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