Pharmacodynamic Evaluation of the Potential Clinical Utility of Fosfomycin and Meropenem in Combination Therapy against KPC-2-Producing Klebsiella pneumoniae

KPC-producing Klebsiella pneumoniae causes serious infections associated with high death rates worldwide. Combination therapy consisting of fosfomycin and a carbapenem is better than monotherapy to combat multidrug-resistant microorganisms, but no dosages for the combination have been defined. The M...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Albiero, James, Sy, Sherwin K. B., Mazucheli, Josmar, Caparroz-Assef, Silvana Martins, Costa, Bruno Buranello, Alves, Janio Leal Borges, Gales, Ana Cristina, Tognim, Maria Cristina Bronharo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914646/
https://ncbi.nlm.nih.gov/pubmed/27139468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03099-15
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