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A Pathogen-Selective Antibiotic Minimizes Disturbance to the Microbiome

Broad-spectrum antibiotic therapy decimates the gut microbiome, resulting in a variety of negative health consequences. Debio 1452 is a staphylococcus-selective enoyl-acyl carrier protein reductase (FabI) inhibitor under clinical development and was used to determine whether treatment with pathogen-...

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Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Yao, Jiangwei, Carter, Robert A., Vuagniaux, Grégoire, Barbier, Maryse, Rosch, Jason W., Rock, Charles O.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914625/
https://ncbi.nlm.nih.gov/pubmed/27161626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00535-16
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