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“The Expanding GRK Interactome: Implications in Cardiovascular Disease and Potential for Therapeutic Development”

Heart failure (HF) is a global epidemic with the highest degree of mortality and morbidity of any disease presently studied. G protein-coupled receptors (GPCRs) are prominent regulators of cardiovascular function. Activated GPCRs are “turned off” by GPCR kinases (GRKs) in a process known as “desensi...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Hullmann, Jonathan, Traynham, Christopher J., Coleman, Ryan C., Koch, Walter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914454/
https://ncbi.nlm.nih.gov/pubmed/27180008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.05.008
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