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The autism associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain

The human MET gene imparts a replicated risk for autism spectrum disorder (ASD), and is implicated in the structural and functional integrity of brain. MET encodes a receptor tyrosine kinase, MET, which plays a pleiotropic role in embryogenesis and modifies a large number of neurodevelopmental event...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Peng, Yun, Lu, Zhongming, Li, Guohui, Piechowicz, Mariel, Anderson, Miranda, Uddin, Yasin, Wu, Jie, Qiu, Shenfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914424/
https://ncbi.nlm.nih.gov/pubmed/26728565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.182
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