Ursolic acid inhibits the growth of human pancreatic cancer and enhances the antitumor potential of gemcitabine in an orthotopic mouse model through suppression of the inflammatory microenvironment

The development of chemoresistance in human pancreatic cancer is one reason for the poor survival rate for patients with this cancer. Because multiple gene products are linked with chemoresistance, we investigated the ability of ursolic acid (UA) to sensitize pancreatic cancer cells to gemcitabine,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Prasad, Sahdeo, Yadav, Vivek R., Sung, Bokyung, Gupta, Subash C., Tyagi, Amit K., Aggarwal, Bharat B.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914350/
https://ncbi.nlm.nih.gov/pubmed/26909608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7537
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