Expression of S1P metabolizing enzymes and receptors correlate with survival time and regulate cell migration in glioblastoma multiforme

A signaling molecule which is involved in proliferation and migration of malignant cells is the lipid mediator sphingosine-1-phosphate (S1P). There are hints for a potential role of S1P signaling in malignant brain tumors such as glioblastoma multiforme (GBM) which is characterized by a poor prognos...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Bien-Möller, Sandra, Lange, Sandra, Holm, Tobias, Böhm, Andreas, Paland, Heiko, Küpper, Johannes, Herzog, Susann, Weitmann, Kerstin, Havemann, Christoph, Vogelgesang, Silke, Marx, Sascha, Hoffmann, Wolfgang, Schroeder, Henry W.S., Rauch, Bernhard H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914339/
https://ncbi.nlm.nih.gov/pubmed/26887055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7366
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