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MicroRNA-138 promotes acquired alkylator resistance in glioblastoma by targeting the Bcl-2-interacting mediator BIM
Glioblastoma is the most aggressive brain tumor in adults with a median survival below 12 months in population-based studies. The main reason for tumor recurrence and progression is constitutive or acquired resistance to the standard of care of surgical resection followed by radiotherapy with concom...
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Pubblicato in: | Oncotarget |
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Autori principali: | , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Impact Journals LLC
2016
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4914333/ https://ncbi.nlm.nih.gov/pubmed/26887050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7346 |
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