High Mobility Group A2 protects cancer cells against telomere dysfunction

The non-histone chromatin binding protein High Mobility Group AT-hook protein 2 (HMGA2) plays important roles in the repair and protection of genomic DNA in embryonic stem cells and cancer cells. Here we show that HMGA2 localizes to mammalian telomeres and enhances telomere stability in cancer cells...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Natarajan, Suchitra, Begum, Farhana, Gim, Jeonga, Wark, Landon, Henderson, Dana, Davie, James R., Hombach-Klonisch, Sabine, Klonisch, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914320/
https://ncbi.nlm.nih.gov/pubmed/26799419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6938
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