High Mobility Group A2 protects cancer cells against telomere dysfunction

The non-histone chromatin binding protein High Mobility Group AT-hook protein 2 (HMGA2) plays important roles in the repair and protection of genomic DNA in embryonic stem cells and cancer cells. Here we show that HMGA2 localizes to mammalian telomeres and enhances telomere stability in cancer cells...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Natarajan, Suchitra, Begum, Farhana, Gim, Jeonga, Wark, Landon, Henderson, Dana, Davie, James R., Hombach-Klonisch, Sabine, Klonisch, Thomas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914320/
https://ncbi.nlm.nih.gov/pubmed/26799419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6938
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