ALK and ROS1 as targeted therapy paradigms and clinical implications to overcome crizotinib resistance

During the past decade, more than 10 targetable oncogenic driver genes have been validated in non-small cell lung cancer (NSCLC). Anaplastic lymphoma kinase (ALK) and ROS1 kinase are two new driver genes implicated in ALK- and ROS1-rearranged NSCLC. Inhibition of ALK and ROS1 by crizotinib has been...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Ye, Mingxiang, Zhang, Xinxin, Li, Nan, Zhang, Yong, Jing, Pengyu, Chang, Ning, Wu, Jianxiong, Ren, Xinling, Zhang, Jian
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Review
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914285/
https://ncbi.nlm.nih.gov/pubmed/26802023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6935
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items