A biodegradable killer microparticle to selectively deplete antigen-specific T cells in vitro and in vivo

The specific eradication of pathogenic T cells for the treatment of allograft rejections and autoimmune disorders without impairment of overall immune function is a fundamental goal. Here, cell-sized poly(lactic-co-glycolic acid) microparticles (PLGA MPs) were prepared as a scaffold to co-display th...

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Udgivet i:Oncotarget
Main Authors: Wang, Wei, Fang, Kun, Li, Miao-Chen, Chang, Di, Shahzad, Khawar Ali, Xu, Tao, Zhang, Lei, Gu, Ning, Shen, Chuan-Lai
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper: Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914277/
https://ncbi.nlm.nih.gov/pubmed/26910923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7519
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