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Decellularized allogeneic intervertebral disc: natural biomaterials for regenerating disc degeneration

Intervertebral disc degeneration is associated with back pain and disc herniation. This study established a modified protocol for intervertebral disc (IVD) decellularization and prepared its extracellular matrix (ECM). By culturing mesenchymal stem cells (MSCs)(3, 7, 14 and 21 days) and human degene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Lin, Xianfeng, Fang, Xiangqian, Wang, Qiang, Hu, Zhijun, Chen, Kai, Shan, Zhi, Chen, Shuai, Wang, Jiying, Mo, Jian, Ma, Jianjun, Xu, Wenbing, Qin, An, Fan, Shunwu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914273/
https://ncbi.nlm.nih.gov/pubmed/26933821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7735
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