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GDF11/BMP11 activates both smad1/5/8 and smad2/3 signals but shows no significant effect on proliferation and migration of human umbilical vein endothelial cells

GDF11/BMP11, a member of TGF-β superfamily, was reported to rejuvenate heart, skeletal muscle and blood vessel architecture in aged mice. However, the rejuvenative effects of GDF11 were questioned recently. Here, we investigated the effects of GDF11 on smad and non-smad signals in human umbilical ve...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhang, Yong-Hui, Cheng, Feng, Du, Xue-Ting, Gao, Jin-Lai, Xiao, Xiao-Lin, Li, Na, Li, Shan-Liang, Dong, De-Li
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914269/
https://ncbi.nlm.nih.gov/pubmed/26919250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7642
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