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SPATIAL: A System-level PAThway Impact AnaLysis approach

The goal of pathway analysis is to identify the pathways that are significantly impacted when a biological system is perturbed, e.g. by a disease or drug. Current methods treat pathways as independent entities. However, many signals are constantly sent from one pathway to another, essentially linkin...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Bokanizad, Behzad, Tagett, Rebecca, Ansari, Sahar, Helmi, B. Hoda, Draghici, Sorin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914126/
https://ncbi.nlm.nih.gov/pubmed/27193997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw429
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