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Tropomodulin3 as the link between insulin-activated AKT2 and cortical actin remodeling in preparation of GLUT4 exocytosis

It is well established that insulin-induced remodeling of actin filaments into a cortical mesh is required for insulin-stimulated GLUT4 exocytosis. Akt2 and its downstream effectors play a pivotal role in mediating the translocation and membrane fusion of GLUT4-storage vesicle (GSV). However, the di...

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Detalles Bibliográficos
Publicado en:Bioarchitecture
Autores principales: Lim, Chun-Yan, Han, Weiping
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4914018/
https://ncbi.nlm.nih.gov/pubmed/26280982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19490992.2015.1031949
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