Efficacy and Safety of ‘Fixed Dose’ versus ‘Loose’ Drug Regimens for Treatment of Pulmonary Tuberculosis in Two High TB-Burden African Countries: A Randomized Controlled Trial

BACKGROUND: There are limited data on the performance of the use of fixed-dose combination (FDC) TB drugs when used under programmatic settings in high TB-endemic countries. We evaluated the efficacy and safety of FDC versus loose formulation (LF) TB treatment regimens for treatment of pulmonary TB...

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Publicado en:PLoS One
Autores principales: Aseffa, Abraham, Chukwu, Joseph N., Vahedi, Mahnaz, Aguwa, Emmanuel N., Bedru, Ahmed, Mebrahtu, Tesfamariam, Ezechi, Oliver C., Yimer, Getnet, Yamuah, Lawrence K., Medhin, Girmay, Connolly, Cathy, Rida, Wasima, Aderaye, Getachew, Zumla, Alimuddin I., Onyebujoh, Philip C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913909/
https://ncbi.nlm.nih.gov/pubmed/27322164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157434
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