Pathophysiology of Motor Dysfunction in Parkinson's Disease as the Rationale for Drug Treatment and Rehabilitation

Cardinal motor features of Parkinson's disease (PD) include bradykinesia, rest tremor, and rigidity, which appear in the early stages of the disease and largely depend on dopaminergic nigrostriatal denervation. Intermediate and advanced PD stages are characterized by motor fluctuations and dysk...

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發表在:Parkinsons Dis
Main Authors: Magrinelli, Francesca, Picelli, Alessandro, Tocco, Pierluigi, Federico, Angela, Roncari, Laura, Smania, Nicola, Zanette, Giampietro, Tamburin, Stefano
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2016
主題:
Review Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4913065/
https://ncbi.nlm.nih.gov/pubmed/27366343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/9832839
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