Pulmonary Th17 anti-fungal immunity is regulated by the gut microbiome()

Commensal microbiota are critical for the development of local immune responses. Here, we show that gut microbiota can regulate CD4 T cell polarization during pulmonary fungal infections. Vancomycin drinking water significantly decreased lung Th17 cell numbers during acute infection, demonstrating t...

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Udgivet i:J Immunol
Main Authors: McAleer, Jeremy P., Nguyen, Nikki L.H., Chen, Kong, Kumar, Pawan, Ricks, David M., Binnie, Matthew, Armentrout, Rachel A., Pociask, Derek A., Hein, Aaron, Yu, Amy, Vikram, Amit, Bibby, Kyle, Umesaki, Yoshinori, Rivera, Amariliz, Sheppard, Dean, Ouyang, Wenjun, Hooper, Lora V., Kolls, Jay K.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912941/
https://ncbi.nlm.nih.gov/pubmed/27217583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502566
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