Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice

BACKGROUND: Endothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) is still unclear. This study was designed to test the hypothesis that metformin...

Full description

Saved in:
Bibliographic Details
Published in:Cardiovasc Diabetol
Main Authors: Yu, Jia-Wen, Deng, Ya-Ping, Han, Xue, Ren, Guo-Fei, Cai, Jian, Jiang, Guo-Jun
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912824/
https://ncbi.nlm.nih.gov/pubmed/27316923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0408-3
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items