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Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice

BACKGROUND: Endothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) is still unclear. This study was designed to test the hypothesis that metformin...

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Detalhes bibliográficos
Publicado no:Cardiovasc Diabetol
Main Authors: Yu, Jia-Wen, Deng, Ya-Ping, Han, Xue, Ren, Guo-Fei, Cai, Jian, Jiang, Guo-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912824/
https://ncbi.nlm.nih.gov/pubmed/27316923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0408-3
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