Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice

BACKGROUND: Endothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) is still unclear. This study was designed to test the hypothesis that metformin...

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Bibliografiske detaljer
Udgivet i:Cardiovasc Diabetol
Main Authors: Yu, Jia-Wen, Deng, Ya-Ping, Han, Xue, Ren, Guo-Fei, Cai, Jian, Jiang, Guo-Jun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912824/
https://ncbi.nlm.nih.gov/pubmed/27316923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-016-0408-3
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