The availability of the embryonic TGF-β protein Nodal is dynamically regulated during glioblastoma multiforme tumorigenesis

BACKGROUND: Glioblastoma (GBM) is the most common primary brain tumor presenting self-renewing cancer stem cells. The role of these cells on the development of the tumors has been proposed to recapitulate programs from embryogenesis. Recently, the embryonic transforming growth factor-β (TGF-β) prote...

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Veröffentlicht in:Cancer Cell Int
Hauptverfasser: Oliveira-Nunes, Maria Cecília, Assad Kahn, Suzana, de Oliveira Barbeitas, Ana Luiza, e Spohr, Tania Cristina Leite de Sampaio, Dubois, Luiz Gustavo Feijó, Ventura Matioszek, Grasiella Maria, Querido, William, Campanati, Loraine, de Brito Neto, José Marques, Lima, Flavia Regina Souza, Moura-Neto, Vivaldo, Carneiro, Katia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
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Primary Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912793/
https://ncbi.nlm.nih.gov/pubmed/27330409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0324-3
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