Modelling of electrokinetic phenomena for capture of PEGylated ribonuclease A in a microdevice with insulating structures

Synthesis of PEGylated proteins results in a mixture of protein-polyethylene glycol (PEG) conjugates and the unreacted native protein. From a ribonuclease A (RNase A) PEGylation reaction, mono-PEGylated RNase A (mono-PEG RNase A) has proven therapeutic effects against cancer, reason for which there...

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Foilsithe in:Biomicrofluidics
Main Authors: Mata-Gomez, Marco A., Perez-Gonzalez, Victor H., Gallo-Villanueva, Roberto C., Gonzalez-Valdez, Jose, Rito-Palomares, Marco, Martinez-Chapa, Sergio O.
Formáid: Artigo
Teanga:Inglês
Foilsithe: AIP Publishing LLC 2016
Ábhair:
SPECIAL TOPIC: SELECTED PAPERS FROM THE 2015 ANNUAL MEETING OF THE AES ELECTROPHORESIS SOCIETY IN SALT LAKE CITY, UTAH (GUEST EDITORS NATHAN SWAMI AND MICHAEL PYCRAFT HUGHES)
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912556/
https://ncbi.nlm.nih.gov/pubmed/27375815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4954197
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