Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis

BACKGROUND AND AIMS: Recently, the number of follicular helper T (Tfh) cells expressing interleukin (IL)-21 was found to increase in peripheral blood of human and murine models of autoimmune hepatitis (AIH). IL-21, the most recently discovered member of the type-I cytokine family, exerts various eff...

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Detalhes bibliográficos
Publicado no:Springerplus
Main Authors: Abe, Kazumichi, Takahashi, Atsushi, Imaizumi, Hiromichi, Hayashi, Manabu, Okai, Ken, Kanno, Yukiko, Watanabe, Hiroshi, Ohira, Hiromasa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912506/
https://ncbi.nlm.nih.gov/pubmed/27386263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40064-016-2512-y
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