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High Throughput, High Resolution Mapping of Protein Localization in Mammalian Brain by In Vivo Genome Editing

A scalable and high-throughput method to identify precise subcellular localization of endogenous proteins is essential for integrative understanding of a cell at the molecular level. Here, we developed a simple and generalizable technique to image endogenous proteins with high specificity, resolutio...

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發表在:Cell
Main Authors: Mikuni, Takayasu, Nishiyama, Jun, Sun, Ye, Kamasawa, Naomi, Yasuda, Ryohei
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912470/
https://ncbi.nlm.nih.gov/pubmed/27180908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.04.044
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