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Identification of a novel mycobacterial arabinosyltransferase activity which adds an arabinosyl residue to α-D-mannosyl residues

The arabinosyltransferases responsible for the biosynthesis of the arabinan domains of two abundant heteropolysaccharides of the cell envelope of all mycobacterial species, lipoarabinomannan and arabinogalactan, are validated drug targets. Using a cell envelope preparation from Mycobacterium smegmat...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Angala, Shiva kumar, McNeil, Michael R., Zou, Lu, Liav, Avraham, Zhang, Junfeng, Lowary, Todd L., Jackson, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912395/
https://ncbi.nlm.nih.gov/pubmed/27045860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b00093
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