Decreased Expression of SETD2 Predicts Unfavorable Prognosis in Patients With Nonmetastatic Clear-Cell Renal Cell Carcinoma

DNA sequencing revealed that mutations in SETD2 occur in 3% to 12% of clear-cell renal cell carcinoma (ccRCC) cases and are associated with poor clinical outcome. In this study, we used an immunohistochemistry (IHC) assay to evaluate the impact of SETD2 loss, with expression of H3K36me3, a nonredund...

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Bibliografiske detaljer
Udgivet i:Medicine (Baltimore)
Main Authors: Liu, Weisi, Fu, Qiang, An, Huimin, Chang, Yuan, Zhang, Weijuan, Zhu, Yu, Xu, Le, Xu, Jiejie
Format: Artigo
Sprog:Inglês
Udgivet: Wolters Kluwer Health 2015
Fag:
7300
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912287/
https://ncbi.nlm.nih.gov/pubmed/26559293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MD.0000000000002004
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