In Vitro and In Vivo Attenuation of Vesicular Stomatitis Virus (VSV) by Phosphoprotein Deletion

Vesicular stomatitis virus (VSV) is highly immunogenic and able to stimulate both innate and adaptive immune responses. However, its ability to induce adverse effects has held back the use of VSV as a potential vaccine vector. In this study we developed VSV-ΔP, a safe yet potent replication-defectiv...

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Udgivet i:PLoS One
Main Authors: Wongthida, Phonphimon, Jengarn, Juggragarn, Narkpuk, Jaraspim, Koonyosying, Pongpisid, Srisutthisamphan, Kanjana, Wanitchang, Asawin, Leaungwutiwong, Pornsawan, Teeravechyan, Samaporn, Jongkaewwattana, Anan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912100/
https://ncbi.nlm.nih.gov/pubmed/27315286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157287
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