In Vitro and In Vivo Attenuation of Vesicular Stomatitis Virus (VSV) by Phosphoprotein Deletion

Vesicular stomatitis virus (VSV) is highly immunogenic and able to stimulate both innate and adaptive immune responses. However, its ability to induce adverse effects has held back the use of VSV as a potential vaccine vector. In this study we developed VSV-ΔP, a safe yet potent replication-defectiv...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Wongthida, Phonphimon, Jengarn, Juggragarn, Narkpuk, Jaraspim, Koonyosying, Pongpisid, Srisutthisamphan, Kanjana, Wanitchang, Asawin, Leaungwutiwong, Pornsawan, Teeravechyan, Samaporn, Jongkaewwattana, Anan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912100/
https://ncbi.nlm.nih.gov/pubmed/27315286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157287
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