In Vitro and In Vivo Attenuation of Vesicular Stomatitis Virus (VSV) by Phosphoprotein Deletion

Vesicular stomatitis virus (VSV) is highly immunogenic and able to stimulate both innate and adaptive immune responses. However, its ability to induce adverse effects has held back the use of VSV as a potential vaccine vector. In this study we developed VSV-ΔP, a safe yet potent replication-defectiv...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Wongthida, Phonphimon, Jengarn, Juggragarn, Narkpuk, Jaraspim, Koonyosying, Pongpisid, Srisutthisamphan, Kanjana, Wanitchang, Asawin, Leaungwutiwong, Pornsawan, Teeravechyan, Samaporn, Jongkaewwattana, Anan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912100/
https://ncbi.nlm.nih.gov/pubmed/27315286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157287
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