In Vitro and In Vivo Attenuation of Vesicular Stomatitis Virus (VSV) by Phosphoprotein Deletion

Vesicular stomatitis virus (VSV) is highly immunogenic and able to stimulate both innate and adaptive immune responses. However, its ability to induce adverse effects has held back the use of VSV as a potential vaccine vector. In this study we developed VSV-ΔP, a safe yet potent replication-defectiv...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Wongthida, Phonphimon, Jengarn, Juggragarn, Narkpuk, Jaraspim, Koonyosying, Pongpisid, Srisutthisamphan, Kanjana, Wanitchang, Asawin, Leaungwutiwong, Pornsawan, Teeravechyan, Samaporn, Jongkaewwattana, Anan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912100/
https://ncbi.nlm.nih.gov/pubmed/27315286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157287
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