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Modeling and gene knockdown to assess the contribution of nonsense-mediated decay, premature termination, and selenocysteine insertion to the selenoprotein hierarchy

The expression of selenoproteins, a specific group of proteins that incorporates selenocysteine, is hierarchically regulated by the availability of Se, with some, but not all selenoprotein mRNA transcripts decreasing in abundance with decreasing Se. Selenocysteine insertion into the peptide chain oc...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Zupanic, Anze, Meplan, Catherine, Huguenin, Grazielle V.B., Hesketh, John E., Shanley, Daryl P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911915/
https://ncbi.nlm.nih.gov/pubmed/27208313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.055749.115
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