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Myeloid thrombomodulin lectin-like domain inhibits osteoclastogenesis and inflammatory bone loss
Osteoclastogenesis is an essential process during bone metabolism which can also be promoted by inflammatory signals. Thrombomodulin (TM), a transmembrane glycoprotein, exerts anti-inflammatory activities such as neutralization of proinflammatory high-mobility group box 1 (HMGB1) through TM lectin-l...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4911607/ https://ncbi.nlm.nih.gov/pubmed/27311356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28340 |
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