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Embryonic Stem Cell Proliferation Stimulated By Altered Anabolic Metabolism From Glucose Transporter 2-Transported Glucosamine

The hexose transporter, GLUT2 (SLC2A2), which is expressed by mouse embryos, is important for survival before embryonic day 10.5, but its function in embryos is unknown. GLUT2 can transport the amino sugar glucosamine (GlcN), which could increase substrate for the hexosamine biosynthetic pathway (HB...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jung, Jin Hyuk, Iwabuchi, Kumiko, Yang, Zhihong, Loeken, Mary R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911601/
https://ncbi.nlm.nih.gov/pubmed/27311888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28452
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