TLR signaling adaptor protein MyD88 in primary sensory neurons contributes to persistent inflammatory and neuropathic pain and neuroinflammation

Increasing evidence suggests that neuro-immune and neuro-glial interactions are critically involved in chronic pain sensitization. It is well studied how immune/glial mediators sensitize pain, but how sensory neurons control neuroinflammation remains unclear. We employed Myd88 conditional knockout (...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Liu, Xing-Jun, Liu, Tong, Chen, Gang, Wang, Bing, Yu, Xiao-Lu, Yin, Cui, Ji, Ru-Rong
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911580/
https://ncbi.nlm.nih.gov/pubmed/27312666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28188
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