Loading...

Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction

We explored the regulation of filaggrin, cyclooxygenase 2 (COX2) and prostaglandin E2 (PGE2) expression induced by urban particulate matter (PM) in human keratinocytes. In addition, we investigated the signaling pathways involved in PM-induced effects on COX2/PGE2 and filaggrin. PMs induced increase...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Lee, Chiang-Wen, Lin, Zih-Chan, Hu, Stephen Chu-Sung, Chiang, Yao-Chang, Hsu, Lee-Fen, Lin, Yu-Ching, Lee, I-Ta, Tsai, Ming-Horng, Fang, Jia-You
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911555/
https://ncbi.nlm.nih.gov/pubmed/27313009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep27995
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!