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Methods for the large-scale synthesis of psoralen furan-side monoadducts and diadducts.

We report methods for the preparation of multimicromole quantities of extremely pure uniquely photo-adducted psoralen-DNA furan-side monoadducts and diadducts (cross-links). The methods use high-intensity krypton and argon ion lasers in the photoreactions and HPLC methods to purify the required olig...

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Autors principals: Spielmann, H P, Sastry, S S, Hearst, J E
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49113/
https://ncbi.nlm.nih.gov/pubmed/1584785
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