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Adoptive transfer of CD8(+) T cells generated from induced pluripotent stem cells triggers regressions of large tumors along with immunological memory

Current approaches to adoptive T cell therapy are limited by the difficulty of obtaining sufficient numbers of T cells against targeted antigens with useful in vivo characteristics. Theoretically, this limitation could be overcome by using induced pluripotent stem cells (iPSCs) that could provide an...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Saito, Hidehito, Okita, Keisuke, Chang, Alfred E., Ito, Fumito
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911287/
https://ncbi.nlm.nih.gov/pubmed/27197199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1742
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