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Engineering Hematopoietic Stem Cells: Lessons from Development

Cell engineering has brought us tantalizingly close to the goal of deriving patient-specific hematopoietic stem cells (HSCs). While directed differentiation and transcription factor-mediated conversion strategies have generated progenitor cells with multilineage potential, to date, therapy-grade eng...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Rowe, R. Grant, Mandelbaum, Joseph, Zon, Leonard I., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911194/
https://ncbi.nlm.nih.gov/pubmed/27257760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.05.016
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