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Engineering Hematopoietic Stem Cells: Lessons from Development

Cell engineering has brought us tantalizingly close to the goal of deriving patient-specific hematopoietic stem cells (HSCs). While directed differentiation and transcription factor-mediated conversion strategies have generated progenitor cells with multilineage potential, to date, therapy-grade eng...

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Bibliographic Details
Published in:Cell Stem Cell
Main Authors: Rowe, R. Grant, Mandelbaum, Joseph, Zon, Leonard I., Daley, George Q.
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911194/
https://ncbi.nlm.nih.gov/pubmed/27257760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.05.016
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